The bcl-2 product is considered to act as an inhibitor of apoptosis. Bcl-2 expression is inhibited in germinal centers where apoptosis forms part of the B cell production pathway. Reactive follicles show no staining for bcl-2, whereas the cells in neoplastic follicles exhibit membrane staining. Bcl-2 a oncoprotein has been shown to inhibit apoptosis.
1ml
| Clone | 100/D5 |
| Isotype | IgG1 |
| Application | IHC |
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