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Species: Mouse Monoclonal
Clone: D33
Isotype: IgG1,k
MW: 58 and 65 to 67 kD
Species Reactivity: Human, Baboon, Monkey, Cow, Cat, Dog, Hamster, Rat and Chicken.
Positive Control: Muscle or sarcoma.

Specificity: This antibody is highly specific to desmin and shows no cross-reaction with other intermediate filament proteins. Antibody to desmin reacts with striated (skeletal and cardiac) as well as smooth muscle cells. In skeletal and cardiac muscles, the staining is confined to the Z-bands giving a characteristic striated appearance. It reacts with leiomyosarcomas (smooth muscle) as well as rhabdomyosarcomas (striated muscle).