p53 acts as both a tumor-suppressor and transcription factor that, upon activation by DNA damage and other cellular stress signals, leads to the transcription of genes triggering cell-cycle arrest, apoptosis, and DNA repair. p53 is overexpressed in over 50% of human cancers. Positive staining of p53 detected by immunohistochemistry has been observed in colon cancer, breast cancer, lung cancer, prostate cancer and ovary cancer.
0.5ml
| Clone | EP9 |
| Isotype | IgG |
| Application | IHC |
| Host | Mouse |
La documentation sera disponible sous peu. En attendant, vous pouvez nous contacter par email à l'adresse specialist@histoline.com
