PD1, or CD279/PDCD1 (programmed cell death-1 protein), is a type I transmembrane receptor expressed on activated T-cells, B-cells, and myeloid cells. Engagement of PD1 by its ligands PD-L1 or PD-L2 transduces a signal that inhibits T-cell proliferation, cytokine production, and cytolytic function. Anti-PDCD1 is a marker of angioimmunoblastic lymphoma.also pro¬duce responses in nonimmunogenic cancers such as non–small-cell lung and colon cancers, broadening their scope beyond classic immunogenic
25 ml
| Clone | DBM15.5 |
| Isotype | IgG1 |
| Application | IHC |
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