This antibody reacts with a protein of 165-170 kDa. Cystic fibrosis transmembrane regulator (CFTR) is composed of two membrane-spanning domains (MSD), two nucleotide-binding domains (NBD) and one R domain. It is structurally similar to multidrug resistance protein (Mdr1). CFTR is found in the apical membranes of epithelia within the pancreas, intestine, bile duct, sweat gland and male genital ducts. CFTR is a valuable marker of human pancreatic duct cell development and differentiation.
0.5ml
| Clone | M3A7 |
| Isotype | IgG1 |
| Application | IHC |
| Host | Mouse |
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